Wildlife Clinic

Species

Cotton mouse

Peromyscus gossypinus

A large, dark woodland mouse of southern swamps and forests that climbs as easily as it runs.

A dark brown cotton mouse slipping through pine straw and green leaves.

Photo Unknown photographer (opens in a new tab) / iNaturalist, CC0 1.0 (opens in a new tab)

At a glance

Size
Body about 9 to 11 cm; tail about 8 to 10 cm
Weight
About 25 to 45 g
Habitat
Bottomland forests, swamps, hammocks, pinewoods and brushy fields across the Southeast
Diet
Seeds, nuts, fruit, insects, spiders and snails
Active
Night
Shelter
Nests in logs, stumps, tree hollows, under bark and in buildings
Lifespan
Usually a year or less in the wild
Rabies vector
No

Identification

Key marks
Large for a mouse; dark brown back, white belly and feet; large eyes and ears; tail dark above and pale below
Told apart from
White-footed mouse, which is smaller and paler; the two can be hard to tell apart
Told apart from
House mouse, which is grey-brown with a scaly tail
Where to look
Swamp forests, stumps and log piles across Georgia

Behaviour

Cotton mice are large, strong-climbing mice of southern forests. They forage at night on the ground and in trees and shrubs for seeds, fruit and insects, and nest in hollow logs, stumps and tree cavities, sometimes well above the ground.

In the South, unlike many northern mice, they breed mostly in the cooler months, with less breeding in the heat of summer.

Why they matter

Cotton mice are among the most common small mammals in southern bottomland forests and swamps, and a major food for owls, snakes, foxes, bobcats and weasels.

One subspecies, the Key Largo cotton mouse of Florida, is endangered, a reminder that even common animals can have fragile local forms.

Reproduction and lifecycle

Breeding — mainly autumn to spring in the South
Gestation — about 23 days
Litter — usually two to five young
Weaning — at about three weeks old
Lifespan — usually less than a year in the wild

Living around people

  • Cotton mice may enter cabins and sheds near woods; closing gaps keeps them out.
  • Like other wild rodents, they can carry diseases; avoid handling them and clean up droppings carefully.
  • Poisons harm the predators that eat mice.

Misconceptions

  • A mouse in the woods is a house mouse gone wild. Cotton mice are native forest animals.
  • Mice cannot climb well. Cotton mice nest and feed in trees.

Related species

Seasonal activity

When this species is breeding, and when there are nests on the ground. Mowing during the shaded months is how most nests are found.

Breeding and active nests by month for this species
JanFebMarAprMayJunJulAugSepOctNovDec
BreedingJan: noFeb: noMar: noApr: noMay: noJun: noJul: noAug: noSep: noOct: noNov: noDec: no
Active nestsJan: noFeb: noMar: noApr: noMay: noJun: noJul: noAug: noSep: noOct: noNov: noDec: no
NotesBreedingBreedingLitters born in hollow logs and stumpsBreeding continuesBreeding slowsLess breeding in summer heatActive at nightActiveBreeding resumesAutumn littersBreedingBreeding

Where it lives

Recorded in 15 states and provinces. Each one links to the other animals there, and to the rehabilitators licensed for them.

If you found one

Answer a few questions and you will get a specific answer for what you are looking at.

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